Synonyms:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate
辛酸七烷-9-基 8-(2-羥乙基)(8-壬氧基)-8-氧辛基)氨基酯
1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate
1-辛基壬(ren)(ren)基8-[(2-羥乙基)[8-(壬(ren)(ren)氧基)-8-氧辛基]氨基]辛酸酯

分子式: C44H87NO5
分子量: 710.17
Storage condition: 2 years -20°C Powder, 2 weeks 4°C in DMSO,6 months -80°C in DMSO

新(xin)型可電離(li)氨基脂質，用(yong)于形成納米脂質遞(di)送系統LNPs，遞(di)送mRNA核酸藥(yao)物(wu)（如新(xin)冠疫苗，基因藥(yao)物(wu)等）。可在嚙齒動物(wu)和靈長類動物(wu)模型中(zhong)提供有效的 mRNA 遞(di)送，顯示(shi)出(chu)最佳的藥(yao)代動力學和無毒副作用(yong)。